Movement Disorders (revue)

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Reversible posterior leukoencephalopathy syndrome in a patient with multiple system atrophy: A possible association with oral midodrine treatment

Identifieur interne : 002C00 ( Main/Exploration ); précédent : 002B99; suivant : 002C01

Reversible posterior leukoencephalopathy syndrome in a patient with multiple system atrophy: A possible association with oral midodrine treatment

Auteurs : Joong-Seok Kim [Corée du Sud] ; Kwang-Soo Lee [Corée du Sud] ; Sung-Chul Lim [Corée du Sud] ; Jae-Young Ahn [Corée du Sud] ; In-Uk Song [Corée du Sud] ; Yeong-In Kim [Corée du Sud] ; Bum-Soo Kim [Corée du Sud] ; Hee-Tae Kim [Corée du Sud]

Source :

RBID : ISTEX:3E05B4D045E3E11D652EDED5E31A85E6EF87F348

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English descriptors

Abstract

We describe a 51‐year‐old man with a 3‐year history of multiple system atrophy, who developed a reversible posterior leukoencephalopathy syndrome (RPLS) after receiving prescription midodrine for therapeutic treatment of orthostatic hypotension. Typical reversible magnetic resonance imaging findings, following treatment with midodrine, suggested a possible relationship between midodrine treatment, supine hypertension, and RPLS, although a cause‐and‐effect relationship cannot be confirmed. © 2007 Movement Disorder Society

Url:
DOI: 10.1002/mds.21461


Affiliations:


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<div type="abstract" xml:lang="en">We describe a 51‐year‐old man with a 3‐year history of multiple system atrophy, who developed a reversible posterior leukoencephalopathy syndrome (RPLS) after receiving prescription midodrine for therapeutic treatment of orthostatic hypotension. Typical reversible magnetic resonance imaging findings, following treatment with midodrine, suggested a possible relationship between midodrine treatment, supine hypertension, and RPLS, although a cause‐and‐effect relationship cannot be confirmed. © 2007 Movement Disorder Society</div>
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